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Life Science Research Professional-2

Company: Stanford Medicine
Location: Milpitas
Posted on: January 13, 2022

Job Description:

Pay Grade: E

FTE: 100%

The Weinacht Laboratory has an opening for a highly motivated and collaborative Life Science Research Professional (LSRP2) with an interest in stem cell biology and development of the adaptive immune system. Successful candidates will join the Pediatric Division of Stem Cell Transplantation and Regenerative Medicine at Stanford University, School of Medicine.

Our research group uses targeted differentiation of induced pluripotent stem cells to reconstruct the developmental signals that drive thymic epithelial cell differentiation. We also apply our stem cell differentiation platform to dissect the mechanistic basis of genetic diseases that perturb thymic development. The ultimate goal of our work is to develop stem cell-derived regenerative thymic tissues as a platform-technology for immunotherapy and to cure patients with thymic defects. As such, candidates with strong biological background and an interest in translational medicine (therapeutic applications of science in medicine) are particularly suitable. The LSRP will learn to generate and characterize induced pluripotent cells (iPSCs), acquire expertise in targeted differentiation techniques, analysis of developmental molecular signatures and signaling pathways. In addition, the applicant has the opportunity to study corresponding murine models.

The LSRP will be a member of a larger research collaborative team that includes stem cell biologists, immunologists, bioengineers and bioinformaticians. Candidates with outstanding personal initiative as well as prior experience in stem cell/molecular/developmental biology, immunology, bioinformatics or related fields are encouraged to apply. This position is suitable for applicants with prior research experience interested in building a competitive resume. Candidates must adhere to highest ethical principles when working with laboratory animals.

Candidates can expect individualized mentorship tailored to their personal career goals and a positive and goal-oriented work environment.

Learn more about our lab here: https://med.stanford.edu/weinachtlaboratory.html .

Duties include:

  • Plan approach to experiments in support of research projects in lab and/or field based on knowledge of scientific theory.
  • Independently conduct experiments; maintain detailed records of experiments and outcomes.
  • Strong TC skills are required; Prior experience working with human ESCs/iPSCs and in vitro differentiation is a plus.
  • Specific duties will include but are not limited to:
    - Tissue culture including maintenance and targeted differentiation of iPSCs, culture of fibroblasts and peripheral blood cells.

    - Animal (mouse) colony management including husbandry, breeding, and genotyping.
    • Apply the theories and methods of a life science discipline to interpret and perform analyses of experiment results; offer suggestions regarding modifications to procedures and protocols in collaboration with senior researcher.
    • Review literature on an ongoing basis to remain current with new procedures and apply learnings to related research.
    • Contribute to publication of findings as needed. Participate in the preparation of written documents, including procedures, presentations, and proposals.
    • Work flexible hours (weekend or holiday tasks are required occasionally)
    • Help with general lab maintenance as needed; maintain lab stock and inventory records up to date, manage chemical inventory and safety records, and provide general lab support as needed.
    • Assist with orientation and training of new staff or students on lab procedures or techniques.

      *- Other duties may also be assigned

      DESIRED QUALIFICATIONS:

      • Bachelor's or Master's degree in related scientific field (e.g. stem cell biology, developmental biology, molecular biology) .
      • Additional experience in related biological field, e.g., immunology or in bioinformatics is very desirable .

        EDUCATION & EXPERIENCE (REQUIRED): Bachelor's degree in related scientific field and two years of relevant work experience; or Master's degree in a related scientific field.

        KNOWLEDGE, SKILLS AND ABILITIES (REQUIRED):

        • Comprehensive understanding of scientific principles.
        • General computer skills and ability to quickly learn and master computer programs, databases, and scientific applications.
        • Strong analytical skills and excellent judgment.
        • Ability to maintain detailed records of experiments and outcomes.
        • Ability to work under deadlines with general guidance is essential.
        • Excellent organizational skills and demonstrated ability to accurately complete detailed work.

          CERTIFICATIONS & LICENSES: None

          PHYSICAL REQUIREMENTS*:
          • Frequently stand, walk, twist, bend, stoop, squat, grasp lightly, use fine manipulation, grasp forcefully, perform desk-based computer tasks, use telephone, write by hand, lift, carry, push and pull objects weighing over 40 pounds.
          • Occasionally sit, kneel, crawl, reach and work above shoulders, sort and file paperwork or parts.
          • Rarely climb, scrub, sweep, mop, chop and mix or operate hand and foot controls.
          • Must have correctible vision to perform duties of the job.
          • Ability to bend, squat, kneel, stand, reach above shoulder level, and move on hard surfaces for up to eight hours.
          • Ability to lift heavy objects weighing up to 50 pounds.
          • Ability to work in a dusty, dirty, and odorous environment.
          • Position may require repetitive motion.
          • Add or subtract physical requirements based on the requirements of your specific job. (remove this statement for posting)

            *- Consistent with its obligations under the law, the University will provide reasonable accommodation to any employee with a disability who requires accommodation to perform the essential functions of his or her job.

            WORKING CONDITIONS:

            • May require working in close proximity to blood borne pathogens.
            • May require work in an environment where animals are used for teaching and research.
            • Position may at times require the employee to work with or be in areas where hazardous materials and/or infectious diseases are present.
            • Employee must perform tasks that require the use of personal protective equipment, such as safety glasses and shoes, protective clothing and gloves, and possibly a respirator.
            • May require extended or unusual work hours based on research requirements and business needs.
              Add or subtract physical requirements based on the requirements of your specific job. (remove this statement for posting

              Additional Information
              • Schedule: Full-time
              • Job Code: 4952
              • Employee Status: Regular
              • Pay Grade: G
              • Department URL: http://pediatrics.stanford.edu/
              • Requisition ID: 91941 As an organization that receives federal funding, Stanford University has a COVID-19 vaccination requirement that will apply to all university employees, including those working remotely in the United States and applicable subcontractors. To learn more about COVID policies and guidelines for Stanford University Staff, please visit https://cardinalatwork.stanford.edu/working-stanford/covid-19/interim-policies/covid-19-surveillance-testing-policy

Keywords: Stanford Medicine, Milpitas , Life Science Research Professional-2, Other , Milpitas, California

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