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Senior Scientist/Principal Scientist, In Vivo Pharmacology

Company: Hengenix Biotech, Inc.
Location: Milpitas
Posted on: June 19, 2022

Job Description:

Hengenix Biotech, Inc., located in Milpitas, CA, focuses on developing and delivering high-quality, innovative, and affordable medicine to patients worldwide to treat a range of chronic and life-threatening diseases with a focus in immune oncology.We are searching for a talented and energetic team player to advance our research projects in our In Vivo Pharmacology group.Responsibilities:

  • Hands-on contribution to planning, design and execution of in vivo pharmacology studies
  • Perform in vivo procedures in mice, including preparation and administration of dosing solutions via different routes, tumor inoculation and measurement, and tissue harvesting
  • Ex vivo analysis of immune cells from various tissues, including collection and processing of multiple tissues and analysis of immune cell phenotype and functionality using multicolor flow cytometry
  • Independently document, analysis, and reporting of animal models (syngeneic and xenograft model, human PBMC model), pharmacokinetic (PK) and pharmacodynamic (PD) studies
  • Work collaboratively with members of the in vivo pharmacology team and provide summaries to project teamsQualifications:
    • Ph.D. degree in the field of immunology, pharmacology, biology or related discipline with 1-3 years industry experience in the preclinical development of cancer immunotherapies
    • Independently plan and execute complex anti-tumor efficacy, PK, and PD studies in mice including: cell culture, dosing (IV, SC, IP), tumor measurement, as well as the dissection of organs for subsequent ex vivo analysis
    • Design flow cytometry (FACS) panels and perform FACS analysis on human and murine cells, tumors, and tissues
    • Excellent verbal and written communication skills, must be highly motivated and work successfully in cross-functional teams by contributing data and ideas

Keywords: Hengenix Biotech, Inc., Milpitas , Senior Scientist/Principal Scientist, In Vivo Pharmacology, Other , Milpitas, California

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