Vice President, Medical Affairs

Company: Alumis Inc.
Location: South San Francisco
Posted on: January 28, 2026

Job Description:

Alumis Inc. is a precision medicines company with the mission to transform the lives of patients with autoimmune diseases. Even with treatment innovations of the last two decades, many patients with immunologic conditions continue to suffer - our goal is to fundamentally change the outcomes for these patients. We have recently completed our pivotal trials of envudeucitinib, our second-generation tyk2 inhibitor in moderate to severe plaque psoriasis and expect results from a potentially pivotal Phase 2b trial in SLE in the third quarter of 2026. As a key member of the Alumis team, you will provide overall leadership for the Medical Affairs function, overseeing Medical Affairs, Field Medical Liaisons, and publications. The position will liaise closely with the clinicians responsible for carrying out Alumis’ clinical studies as well as our commercial group. Applicants should be a “leader/doer” capable of generating strategies and leading cross functionally. This VP, Medical Affairs will report directly to the Chief Medical Officer. Responsibilities Lead the Medical Affairs function at Alumis Develop and implement key Medical Affairs strategies and activities to support the development of our lead assets Continue to build and scale the Medical Affairs organization Develop and present Medical Affairs operational plans to Development and Executive management Represent company externally Direct and oversee all aspects of Medical Affairs and pre-launch needs Lead medical launch preparations for our lead Psoriasis candidate, ensuring the scientific narrative is robust and well-vetted. As a member of the Development Leadership Team, run and continue to build the Medical Affairs function Build and lead a best-in-class global medical affairs team to support launches of multiple indications with a focus on psoriasis for our lead asset, envudeucitinib Develop key performance indicators and generate analytical reports related to Medical Affairs plans and Medical Science Liaison group activities Develop and implement Medical Communication and Disease State Awareness strategies Partner with KOLs to gather information on current focused therapeutic area issues and questions Collaborate with the Commercial team to develop educational material for providers and patients that are balanced and medically accurate Provide direction and input into the development and implementation of successful reimbursement and market-access strategies Work closely with the members of the clinical development and commercial leadership teams to develop the overall strategic direction for Alumis, evaluate alternative strategies, identify competitive issues, and develop and implement operating plans to achieve company objectives Foster collaborative relationships with academic and clinical experts, publishers, medical and patient associations, and other relevant external and internal stakeholders Develop and manage departmental budgets that effectively achieve desired goals and are balanced with the financial objectives of the broader organization Oversee the publication strategy, ensuring clinical data is presented at major congresses (e.g., AAD, EADV, ACR) and in high-impact peer-reviewed journals. Education | Experience | Skill Requirements 10 years of professional experience within Biotech/Pharma in Medical Affairs 5 years of people leadership experience An understanding of government and industry guidelines, regulations, laws, etc., for appropriate scientific/medical exchange and communication with customers Ability to lead by example, attract and develop talent, build interdependent partnerships, and create a culture of collaboration and teamwork that fosters open communication, constructive conflict resolution and organizational flexibility Ability to prioritize and manage several complex projects simultaneously Proven ability to develop internal relationships in a highly matrixed environment, as well as external relationships with Key Opinion Leaders and industry experts Ability to communicate effectively at all levels and present complex and/or new ideas with clarity and simplicity Ability to prioritize concurrent projects with tight deadlines and operate in a highly compliance-driven environment Excellent written, verbal, and interpersonal skills, and the ability to communicate at all levels within the company Travel (25-40%) may be required to represent the company at medical conferences, presentations, and other meetings Our headquarters are located in the San Francisco Bay Area and regular presence at headquarters is required Extensive prior experience in dermatology, particularly psoriasis is required. Prior experience in SLE is highly desirable. Prior experience taking a product form Phase 3 to a successful launch is also highly desirable. Advanced degree (PharmD, Ph.D. or MD) is required, MD is preferred. The salary range for this position is $315,000 USD to $370,000 USD annually. This salary range is an estimate, and the actual salary may vary based on the Company’s compensation practices.

Keywords: Alumis Inc., Milpitas , Vice President, Medical Affairs, Science, Research & Development , South San Francisco, California